Smoking, obesity, treatment duration, and pre-existing cardiac diseases may contribute to the development of cardiotoxicity among patients with cancer who are undergoing 5-fluorouracil (5-FU) chemotherapy, suggests a recent study. “[W]ell-defined risk factors and their possible mechanisms should be identified and evaluated on a clinical basis and put together into a model for risk stratification, which could …

Obesity, smoking tied to 5-FU-induced cardiotoxicity in cancer patients Read More »

Hypertensive disorders of pregnancy (HDPs) appear to increase the odds of adverse neurodevelopmental and cognitive outcomes, such as autism and attention-deficit/hyperactivity disorder (ADHD), in the offspring, suggest the results of a meta-analysis. The mechanisms driving these associations remain unclear, but the findings point to a group of children who will benefit from early intervention and support …

Hypertensive disorders of pregnancy may impair childhood neurodevelopment Read More »

o The use of a noninvasive bivariate model can accurately predict blood pressure (BP) response at 6 and 12 months after renal denervation (RDN) in patients with resistant hypertension, a study has shown. The authors carried out a predefined secondary analysis from a prospective single-centre trial among patients with resistant hypertension undergoing ultrasound-based RDN. They …

Noninvasive model predicts BP decrease post-RDN for arterial hypertension Read More »

New research suggests that having a consistent sleep schedule may decrease the risks of depression and anxiety, regardless of the duration of sleep. Analysis of data from the UK Biobank showed that compared with irregular sleepers, regular sleepers had a 38-percent lower risk of depression (hazard ratio [HR], 0.62, 95 percent confidence interval [CI], 0.52–0.73) …

Sleep regularity matters for mental health Read More »

25 At the recent COVID-CONNECT Masterclass, an expert-led session explored where COVID-19 stands among common viral infections today. In a non-promotional symposium supported by Pfizer, infectious disease specialist Dr Leong Hoe Nam, Mount Elizabeth Hospital Novena, Singapore, discussed strategies for managing viral infections and surge preparedness. Complementing this, Professor David Strain from the University of …

COVID-19 and beyond: Viral infections, preparedness, and long-term impact Read More »