Beyond Survival: Empowering a Future for Patients with EGFR-Mutated NSCLC

The growing range of treatment options for EGFR-mutated non-small cell lung cancer (NSCLC) has made first-line decisions more complex and more critical. Patients are increasingly more aware of new and different treatment options and are seeking therapies that align with their personal values. As survival outcomes continue to improve, shared decision-making (SDM) plays a vital …

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What’s new, what’s hot in diabetes management: Snippets from ATTD-ASIA

ATTD-ASIA 2024, held recently in Singapore, was a huge success, with nearly 800 delegates from 49 countries gracing the event. ATTD-Asia 2024 chair, Professor Moshe Phillip, said the event brought together top diabetes experts to ensure patients can access the latest technologies and treatments for diabetes. MIMS Doctor reports highlights and snippets from the conference. Resources

Protecting the vulnerable: The role of oral antivirals in COVID-19 management

At the Asia Vaccines and Antivirals Summit (AVAS) 2025 held in Bangkok, Thailand, two expert-led sessions provided valuable perspectives on the expanding role of oral antivirals in COVID-19 management. Dr Daniel Griffin, an infectious disease specialist and Clinical Instructor of Medicine at Columbia University, New York, US, focused on protecting high-risk populations through the timely …

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Remote AF screening with ECG patch nudges up diagnosis numbers

A remote screening method using a wearable ECG patch yields a modest increase in atrial fibrillation (AF) diagnoses among older adults at risk of stroke, according to the AMALFI trial. The rate of AF detection at 2.5 years was 6.8 percent in the ECG patch arm vs 5.4 percent in the usual care arm, translating …

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Inclisiran-based strategy achieves LDL-C goals in patients at high CV risk

Prof Ulf Landmesser Treatment with inclisiran, on top of individually optimized lipid-lowering therapy (ioLLT), resulted in the achievement of guideline-recommended low-density lipoprotein cholesterol (LDL-C) goals among patients with hypercholesterolaemia at high or very high risk of cardiovascular (CV) events, according to the VICTORION-Difference trial presented at ESC 2025. “The study met its primary endpoint, demonstrating the superiority …

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Amlodipine-telmisartan-chlorthalidone combo promises better BP-lowering effect

A low-dose combination therapy, AD-209, that includes telmisartan 20 mg, amlodipine 2.5 mg, and chlorthalidone 6.25 mg demonstrates efficacy in lowering high blood pressure (BP) when compared with telmisartan alone in patients with essential hypertension, reports a study presented at ESC 2025. This multicentre, randomized, double-blinded, parallel, phase III clinical trial also notes a comparable safety profile …

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Semaglutide, dulaglutide help prevent cognitive decline in HF patients

Treatment with semaglutide and dulaglutide results in a significantly lower risk of adverse cognitive decline in patients with heart failure (HF), as shown by the results of a retrospective cohort study using real-world data. “Semaglutide and dulaglutide were associated with reduced cognitive decline in heart failure, particularly vascular dementia,” said lead author Andreas Kalogeropoulus, associate professor at …

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New model predicts critical admission in children with dengue

A recently developed model demonstrates its utility in predicting critical care entrance among children with dengue. The development and internal validation of the predictive model involved a total of 1,385 patients. In temporal validation with 519 additional participants, the c-statistic was 0.82 (95 percent confidence interval [CI], 0.77–0.87), and the calibration slope was 0.98 (95 …

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Mediterranean–DASH diet improves health outcomes in T2D, hypertension

Adherence to the Mediterranean–Dietary Approaches to Stop Hypertension (DASH) diet leads to improvements in anthropometric, laboratory parameters, and blood pressure (BP) in patients with type 2 diabetes (T2D) and hypertension, reports a study. This intervention also improves satiety levels throughout the day. On the other hand, consumption of ultra-processed foods results in worse parameters. Eighty-four …

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